Yes, but you need to set an environment variable for this: Custom play launch commands by tong · Pull Request #2605 · armory3d/armory · GitHub.
As for using Internet Explorer, I guess one can expect that things don’t run as smoothly there. Kha has some IE specific code, but I think it’s not tested very well and I’m not sure if anyone still cares about it… I wouldn’t be surprised if Rob (the Kha developer) decides to drop support for it now that Microsoft doesn’t support it anymore.